Total synthesis of indole and dihydroindole alkaloids. X.1,2 The preparation of novel oxygenated catharanthine derivatives
- 15 September 1977
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 55 (18) , 3227-3234
- https://doi.org/10.1139/v77-449
Abstract
Detailed investigations involving the electrophilic attack of various reagents on the 3,4-double bond of catharanthine [Catharanthus roseus] derivatives (e.g., R = O) furnished a series of novel derivatives of potential use in the syntheses of naturally occurring bisindole alkaloids. These studies include such reagents as peracid, osmium tetroxide and positive iodine.Keywords
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