Identification of hydrazine derived from hydralazine in experimental animals.
- 1 January 1979
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 27 (8) , 1938-1941
- https://doi.org/10.1248/cpb.27.1938
Abstract
The liberation of hydrazine from hydralazine was demonstrated in rabbit urine, in rat plasma and in a rat enzyme system. The identification of hydrazine in rabbit urine was performed by comparison of the gas chromatogram and mass spectrum of its benzalazine derivative with those of an authentic sample. Small amounts of hydrazine extracted from rat plasma and the rat enzyme system were detected by mass fragmentography using 15N-hydrazine.This publication has 1 reference indexed in Scilit:
- Quantitative determination of hydrazines derived from isoniazid in man.CHEMICAL & PHARMACEUTICAL BULLETIN, 1977