5-Aza-2′-deoxycytidine Activates the p53/p21Waf1/Cip1 Pathway to Inhibit Cell Proliferation
Open Access
- 1 April 2004
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 279 (15) , 15161-15166
- https://doi.org/10.1074/jbc.m311703200
Abstract
No abstract availableKeywords
This publication has 47 references indexed in Scilit:
- Increased expression of unmethylated CDKN2D by 5-aza-2′-deoxycytidine in human lung cancer cellsOncogene, 2001
- DNA Methyltransferase Inhibition in Normal Human Fibroblasts Induces a p21-dependent Cell Cycle WithdrawalPublished by Elsevier ,2001
- DNA Methyltransferase Inhibition Induces the Transcription of the Tumor Suppressor p21Journal of Biological Chemistry, 2000
- Regulation of p53 in response to DNA damageOncogene, 1999
- Disruption of p53 in human cancer cells alters the responses to therapeutic agentsJournal of Clinical Investigation, 1999
- p16INK4 Expression Is Associated with the Increased Sensitivity of Human Non‐small Cell Lung Cancer Cells to DNA Topoisomerase I InhibitorsJapanese Journal of Cancer Research, 1997
- Pharmacological approach for optimization of the dose schedule of 5-Aza-2’-deoxycytidine (Decitabine) for the therapy of leukemiaLeukemia, 1997
- Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinasesNature, 1995
- Definition of a consensus binding site for p53Nature Genetics, 1992
- High-performance Liquid Chromatographic Analysis of Chemical Stability of 5-aza-2′-DeoxycytidineJournal of Pharmaceutical Sciences, 1981