A Transition to a Compact Form of DNA in Polymer Solutions
- 1 August 1971
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 68 (8) , 1886-1890
- https://doi.org/10.1073/pnas.68.8.1886
Abstract
In the presence of over-threshold concentrations of simple neutral polymers and salts, DNA undergoes a cooperative change in its solution structure. Sedimentation studies at low DNA concentrations show that phage DNA molecules collapse into particles approaching the compactness of the contents of phage heads. The interaction between DNA and polymers is thought to be nonspecifically replusive.Keywords
This publication has 6 references indexed in Scilit:
- Molecular weights of coliphages and coliphage DNA: II. Measurement of diffusion coefficients using optical mixing spectroscopy, and measurement of sedimentation coefficientsJournal of Molecular Biology, 1970
- Collapse of single DNA molecules in ethanolJournal of Molecular Biology, 1969
- CRYSTALLIZATION OF DNA FROM DILUTE SOLUTIONProceedings of the National Academy of Sciences, 1969
- Flexibility of native DNA from the sedimentation behavior as a function of molecular weight and temperatureJournal of Molecular Biology, 1968
- Sedimentation coefficient of polyoma virus DNABiopolymers, 1967
- Sedimentation studies of the size and shape of DNAJournal of Molecular Biology, 1965