Effects of Difenamizole on Content of Catecholamines and Metabolites in Mouse Brain
Open Access
- 1 January 1978
- journal article
- research article
- Published by Elsevier in The Japanese Journal of Pharmacology
- Vol. 28 (4) , 642-646
- https://doi.org/10.1254/jjp.28.642
Abstract
The effects of analgesic doses of DFZ [difenamizole] on cerebral catecholamines and their metabolites were investigated in mice. DFZ decreased not only the concentration of 3-methoxytyramine but also the concentration of HVA [homovanillic acid] in the striatum. These results suggest that the mechanisms by which CPZ [chlorpromazine] and DFZ depress catecholaminergic neurons differ.This publication has 13 references indexed in Scilit:
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