Incomplete replication of human parainfluenza virus type 2 in mouse L929 cells
- 1 March 1989
- journal article
- research article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 108 (1-2) , 137-144
- https://doi.org/10.1007/bf01313751
Abstract
Human parainfluenza virus type 2 (HPIV-2) was tested for its ability to replicate in murine L929 cells. L929 cells were non-permissive for replication of HPIV-2. Interferon produced endogenously played no role in its incomplete replication. The mechanism by which growth of HPIV-2 was suppressed in L929 cells was studied. Synthesis of virus-specific polypeptides, particularly glycoprotein(s), was suppressed in HPIV-2-infected L929 cells. The HN mRNA could scarcely be detected in virus-infected L929 cells.Keywords
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