Effect of Physical Activity on Cognitive Function in Older Adults at Risk for Alzheimer Disease
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Open Access
- 3 September 2008
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 300 (9) , 1027-1037
- https://doi.org/10.1001/jama.300.9.1027
Abstract
As the world population ages, the number of older adults living with Alzheimer disease (AD) is estimated to increase from the current 26.6 million to 106.2 million by 2050.1 If illness onset could be delayed by 12 months, 9.2 million fewer cases of AD would occur worldwide.1 For this reason, attempts have been made to identify individuals who are at increased risk of AD and to test interventions that might delay the progression of prodromal symptoms to full-blown dementia. The results from observational studies suggest that older people who are free of dementia but report memory decline or show objective evidence of cognitive impairment are more likely to develop AD over time.2,3Keywords
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