A Rapid Synthesis of 2,3,11,11a-Tetrahydro-6H-pyrazino[1,2-b]isoquinoline-1,4-diones Through an Amido Iminium Ion Cyclization
- 1 January 1990
- journal article
- research article
- Published by CSIRO Publishing in Australian Journal of Chemistry
- Vol. 43 (4) , 773-775
- https://doi.org/10.1071/ch9900773
Abstract
7,10-Dimethoxy-6-methyl-2,3,11,11a-tetrahydro-6H-pyrazino[1,2-b]isoquinoline-1,4-diones (5) and (6) were synthesized from glycine anhydride and 2,5-dimethoxybenzaldehyde through an amido iminium ion cyclization reaction. This method for the construction of the tetrahydroisoquinoline ring will be useful for the synthesis of saframycins.Keywords
This publication has 0 references indexed in Scilit: