An enzymatically stable kyotorphin analog induces pain in subattomol doses☆
- 31 May 2000
- Vol. 21 (5) , 717-722
- https://doi.org/10.1016/s0196-9781(00)00190-x
Abstract
No abstract availableKeywords
This publication has 12 references indexed in Scilit:
- Low dose of kyotorphin (tyrosine–arginine) induces nociceptive responses through a substance P release from nociceptor endingsMolecular Brain Research, 1999
- In Vivo Molecular Signal Transduction of Peripheral Mechanisms of PainThe Japanese Journal of Pharmacology, 1999
- Orphanin FQ: A Neuropeptide That Activates an Opioidlike G Protein-Coupled ReceptorScience, 1995
- Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptorNature, 1995
- Systemic analgesic activity and .delta.-opioid selectivity in [2,6-dimethyl-Tyr1, D-Pen2, D-Pen5]enkephalinJournal of Medicinal Chemistry, 1992
- Solid phase synthesis of peptides containing the CH2NH peptide bond isosterePeptides, 1987
- Degradation of kyotoprhin by a purified membrane-bound-aminopeptidase from monkey brain: Potentiation of kyotorphin-induced analgesia by a highly effective inhibitor, bestatinLife Sciences, 1985
- Ethical guidelines for investigations of experimental pain in conscious animalsPAIN®, 1983
- A novel analgesic dipeptide from bovine brain is a possible Met-enkephalin releaserNature, 1979
- The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and catsPain, 1977