Influence of the Genotype on the Clinical Course of the Long-QT Syndrome
- 1 October 1998
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 339 (14) , 960-965
- https://doi.org/10.1056/nejm199810013391404
Abstract
The congenital long-QT syndrome, caused by mutations in cardiac potassium-channel genes (KVLQT1 at the LQT1 locus and HERG at the LQT2 locus) and the sodium-channel gene (SCN5A at the LQT3 locus), has distinct repolarization patterns on electrocardiography, but it is not known whether the genotype influences the clinical course of the disease.Keywords
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