Age-Related Macular Degeneration

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Abstract
Age-related macular degeneration, a deterioration of the central portion of the retina, is the chief cause of severe and irreversible loss of vision in developed countries.1,2 There is no effective treatment for most patients with age-related macular degeneration, and many patients therefore resort to experimental treatments. Physicians must know how to counsel their patients about the limitations and risks of these experimental therapies. Fortunately, several clinical trials sponsored by both the National Eye Institute and the private sector are evaluating novel prophylactic and therapeutic interventions. In addition, there is much exciting, ongoing basic research, some of which may lead . . .