Diffusion approximations of the two-locus Wright-Fisher model
- 1 February 1989
- journal article
- Published by Springer Nature in Journal of Mathematical Biology
- Vol. 27 (1) , 17-28
- https://doi.org/10.1007/bf00276078
Abstract
Diffusion approximations are established for the multiallelic, two-locus Wright-Fisher model for mutation, selection, and random genetic drift in a finite, panmictic, monoecious, diploid population. All four combinations of weak or strong selection and tight or loose linkage are treated, though the proof in the case of strong selection and loose linkage is incomplete. Under certain conditions, explicit formulas are obtained for the stationary distributions of the two diffusions with loose linkage.Keywords
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