Hepatic leptin signaling in obesity
Open Access
- 23 March 2005
- journal article
- fj express-summaries
- Published by Wiley in The FASEB Journal
- Vol. 19 (8) , 1048-1050
- https://doi.org/10.1096/fj.04-2846fje
Abstract
Obesity, a state of apparent “leptin resistance,” is well known to be associated with insulin resistance. In diet-induced obesity (DIO), hepatic insulin signaling is impaired but the link between lep...Keywords
Funding Information
- International Foundation for Science
This publication has 31 references indexed in Scilit:
- Leptin Increases Hepatic Insulin Sensitivity and Protein Tyrosine Phosphatase 1B ExpressionMolecular Endocrinology, 2004
- Leptin Signaling in the Central Nervous System and the PeripheryRecent Progress in Hormone Research, 2004
- Analysis of paradoxical observations on the association between leptin and insulin resistanceThe FASEB Journal, 2002
- Leptin signallingCellular Signalling, 2002
- Leptin Induces Insulin-like Signaling That Antagonizes cAMP Elevation by Glucagon in HepatocytesJournal of Biological Chemistry, 2000
- LeptinAnnual Review of Physiology, 2000
- Selective interaction between leptin and insulin signaling pathways in a hepatic cell lineProceedings of the National Academy of Sciences, 2000
- Acute effects of leptin on glucose metabolism of in situ rat perfused livers and isolated hepatocytesInternational Journal of Obesity, 1999
- Acute Effect of Leptin on Hepatic Glycogenolysis and Gluconeogenesis in Perfused Rat LiverHepatology, 1999
- Positional cloning of the mouse obese gene and its human homologueNature, 1994