Sex hormones and oesophageal adenocarcinoma: influence of childbearing?
Open Access
- 27 September 2005
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 93 (8) , 859-861
- https://doi.org/10.1038/sj.bjc.6602810
Abstract
The male predominance of oesophageal adenocarcinoma might be explained by oestrogen protection in women. If true, female patients might have sex hormonal disturbances rendering impaired fertility. The influence of childbearing on the risk of oesophageal adenocarcinoma was investigated in a Swedish population-based case (n=63) -control (n=141) study. Childless women were not at increased risk compared to childbearing (OR=0.82; 95% CI=0.25–2.72), as neither were women with 0–1 children compared to women with at least three children (OR=0.93; 95% CI=0.35–2.49). In conclusion, we found no inverse assciation between childbearing and oesophageal adenocarcinoma.Keywords
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