Mobilization of the gentamicin resistance gene in Enterococcus faecalis
Open Access
- 1 June 1990
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 34 (6) , 1278-1280
- https://doi.org/10.1128/aac.34.6.1278
Abstract
Enterococcus faecalis plasmid pBEM10 (a conjugative plasmid encoding beta-lactamase production and gentamicin resistance [Gmr]) was made transfer deficient by using Tn917. Relocation of the Gmr determinant into two sites on pCF10 was observed. Restriction analysis revealed insertion of a common 2.5-kilobase-pair HindIII and a 3.9-kilobase-pair HaeIII fragment encoding Gmr, suggesting that this determinant resides on a transposon similar to Tn4001.This publication has 23 references indexed in Scilit:
- Mobility of gentamicin resistance genes from staphylococci isolated in the United States: identification of Tn4031, a gentamicin resistance transposon from Staphylococcus epidermidisAntimicrobial Agents and Chemotherapy, 1989
- The aacA-aphD Gentamicin and Kanamycin Resistance Determinant of Tn4001 from Staphylococcus aureus: Expression and Nucleotide Sequence AnalysisMicrobiology, 1987
- Detection and Characterization of IS256, an Insertion Sequence in Staphylococcus aureusMicrobiology, 1987
- Chromosome- and plasmid-mediated gentamicin resistance in Staphylococcus aureus encoded by Tn4001Journal of Medical Microbiology, 1987
- Plasmid-mediated resistance to gentamicin in Staphylococcus aureus: the involvement of a transposonJournal of Medical Microbiology, 1987
- Transferable beta-lactamase. A new mechanism for in vitro penicillin resistance in Streptococcus faecalis.Journal of Clinical Investigation, 1983
- Kinetic Studies of Aminoglycoside Acetyltransferase and Phosphotransferase from Staphylococcus aureus RPALEuropean Journal of Biochemistry, 1983
- High-Level Resistance to Gentamicin in Clinical Isolates of EnterococciThe Journal of Infectious Diseases, 1983
- Aminoglycoside-modifying enzyme content of a multiply resistant strain of Streptococcus faecalisJournal of Antimicrobial Chemotherapy, 1983
- Direct stimulation of the transfer of antibiotic resistance by sex pheromones in Streptococcus faecalisPlasmid, 1981