Abstract
Serum from DDT-prostrate American cockroaches, Periplaneta americana (L.) (Orthoptera: Blattidae), injected into previously untreated cockroaches caused an increase in trehalose content. This effect was not observed with scrum from DDE-treated cockroaches. The hyperglycemic activity is present in serum mainly from the prostrate stages of DDT poisoning. The agent is stable to heating and is stable at room temperature for as long as 4 hours. The active fractions from molecular sieve chromatography are distinct from the bulk of the serum protein. The physiological significance of this agent is discussed.

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