EVIDENCE FOR A MAJOR ADDITIVE GENE IN ULCERATIVE-COLITIS

  • 1 December 1989
    • journal article
    • research article
    • Vol. 36  (6) , 411-414
Abstract
Complex segregation analysis of 124 families with ulcerative colitis with two or more affected individuals suggests a rare additive major gene causing the disease with about 20% affected among the heterozygotes for the gene. There was no evidence for multifactorial inheritance.