Impaired pancreatic polypeptide release in chronic pancreatitis with steatorrhoea.
Open Access
- 1 February 1979
- Vol. 20 (2) , 98-101
- https://doi.org/10.1136/gut.20.2.98
Abstract
Pancreatic polypeptide (PP) is a newly discovered hormonal peptide localised in a distinct endocrine cell type in the pancreas. PP circulates in plasma and in normal subjects levels rise substantially on the ingestion of food (mean rise 138 pmol/l). In 10 patients with chronic pancreatitis with exocrine deficiency the PP response to a test breakfast was greatly reduced (mean rise 20 pmol/l, P less than 0.001). PP response to the meal was normal in 10 patients with active coeliac disease and 12 patients with acute tropical sprue with steatorrhoea.This publication has 11 references indexed in Scilit:
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