A Clinical Trial of the Efficacy and Acceptability of d-Fenfluramine in the Treatment of Neuroleptic-induced Obesity
- 1 August 1988
- journal article
- research article
- Published by Royal College of Psychiatrists in The British Journal of Psychiatry
- Vol. 153 (2) , 208-213
- https://doi.org/10.1192/bjp.153.2.208
Abstract
Twenty-nine overweight schizophrenic patients maintained on depot neuroleptic injections who wished to lose weight took part in a double-blind, placebo-controlled trial of 30 mg D-fenfluramine. All subjects received dietary advance. Sixteen patients completed the 12-week trial. Rate of weight loss was significantly greater in those taking D-fenfluramine. Side-effects were reported, but no deterioration in mental state was noted.Keywords
This publication has 10 references indexed in Scilit:
- Prevalence of Obesity in Patients Receiving Depot AntipsychoticsThe British Journal of Psychiatry, 1988
- D-Fenfluramine selectively suppresses carbohydrate snacking by obese subjectsInternational Journal of Eating Disorders, 1985
- LONG-TERM EFFICACY OF FENFLURAMINE IN TREATMENT OF OBESITYThe Lancet, 1983
- CONTROLLED TRIAL OF BEHAVIOUR THERAPY, PHARMACOTHERAPY, AND THEIR COMBINATION IN THE TREATMENT OF OBESITYThe Lancet, 1980
- Studies on fenfluramhe as an anti-obesity agentCurrent Medical Research and Opinion, 1979
- Plasma fenfluramine levels, weight loss, and side effects.BMJ, 1977
- Leukaemoid reactions associated with fulminating ulcerative colitisPublished by Oxford University Press (OUP) ,1975
- Reinforcement and Weight Loss in SchizophrenicsPsychological Reports, 1972
- Gas chromatographic measurement of levels of fenfluramine and norfenfluramine in human plasma red cells and urine following therapeutic dosesJournal of Chromatography A, 1970
- The Brief Psychiatric Rating ScalePsychological Reports, 1962