Biochemical Methods in Enantioselective Synthesis of Bioactive Natural Products
- 1 November 1995
- journal article
- account
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1995 (11) , 1097-1109
- https://doi.org/10.1055/s-1995-5191
Abstract
Hydrolytic enzymes and microorganisms were employed in enantioselective syntheses of bioregulators such as hormones and pheromones. Esterases and lipases were useful in achieving optical resolution, conversion of meso-compounds to optically active compounds, and macrolactonization. Yeasts provided a variety of optically active hydroxy ketones and esters, which served as versatile non-racemic chiral building blocks.Keywords
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