Orally bioavailable, indole-based nonpeptide GnRH receptor antagonists with high potency and functional activity

This publication has 27 references indexed in Scilit:

• Synthesis of chiral β-methyl tryptamine-derived GnRH antagonists
  Tetrahedron Letters, 2001
• Substituted Indole-5-carboxamides and -acetamides as Potent Nonpeptide GnRH Receptor Antagonists
  Bioorganic & Medicinal Chemistry Letters, 2001
• Potent nonpeptide GnRH receptor antagonists derived from substituted indole-5-carboxamides and -acetamides bearing a pyridine side-chain terminus
  Bioorganic & Medicinal Chemistry Letters, 2001
• 2-(3,5-Dimethylphenyl)tryptamine Derivatives that Bind to the GnRH Receptor
  Bioorganic & Medicinal Chemistry Letters, 2001
• Heterocyclic Derivatives of 2-(3,5-Dimethylphenyl)tryptamine as GnRH Receptor Antagonists
  Bioorganic & Medicinal Chemistry Letters, 2001
• Initial structure–activity relationship of a novel class of nonpeptidyl GnRH receptor antagonists: 2-arylindoles
  Bioorganic & Medicinal Chemistry Letters, 2001
• SAR studies of novel 5-substituted 2-arylindoles as nonpeptidyl GnRH receptor antagonists
  Bioorganic & Medicinal Chemistry Letters, 2001
• Progress towards the development of non-peptide orally-active gonadotropin-releasing hormone (GnRH) antagonists: therapeutic implications
  British Medical Bulletin, 2000
• Discovery of a Novel, Potent, and Orally Active Nonpeptide Antagonist of the Human Luteinizing Hormone-Releasing Hormone (LHRH) Receptor
  Journal of Medicinal Chemistry, 1998
• Chemistry and Molecular Biology in the Search for New LHRH Antagonists
  Angewandte Chemie International Edition in English, 1997