Choreo-athetosis and Encephalopathy Induced by Phenytoin
- 27 April 1974
- Vol. 2 (5912) , 204-205
- https://doi.org/10.1136/bmj.2.5912.204
Abstract
Two patients with intractable epilepsy who had been treated with various combinations of anticonvulsant drugs developed phenytoin encephalopathy. In both patients choreo-athetoid involuntary movements were prominent. Blood phenytoin concentrations were above 30 μg/ml. When phenytoin was given in smaller doses and its level in the blood fell the involuntary movements and other clinical manifestations disappeared.Keywords
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