The study of calcification of mammalian cartilage in norm and pathology by stain historadiography

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Abstract
The combined technique of histology and radiography — stain historadiography (Bohatirchuk, '57a) — was used for studies of cartilage calcification. The main advantages of the technique are: a. X‐ray specificity in the detection of calcium; b. the possibility of a morphological visualization of calcium in biological tissues at a microlevel. Three patterns of cartilage calcification were observed: 1. columnar; 2. expansive; 3. ubiquitous. Stain historadiographs suggest that the cartilage cell rather actively participates in the calcification: a. calcium deposits are often found within the cytoplasm and cell membrane; b. some cartilage cells are frequently entombed in intraosseous lacunae. The latter phenomenon is especially often observed in the ubiquitous type of calcification.