ADVERSE REACTIONS TO INTRAVASCULARLY ADMINISTERED CONTRAST MEDIA

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Abstract
Case reports on 112,003 patients obtained through a prospective survey have been studied and submitted to computer processing. The significant findings have been reviewed and their importance discussed.The following points are noteworthy: the value of pretesting is doubtful; and routine pretesting is not a recommended procedure.The constant readiness of a fully equipped emergency tray offers far greater security and assurance of patient safety than the unpredictable and unreliable results of pretesting.The over-all incidence of nonfatal reactions is lower than has been previously indicated: 5.65 per cent for intravenous urography; and 2.33 per cent for intravascular studies. The incidence of fatal reaction (1 in 10,000) is higher than that reported on the basis of retrospective studies. This figure may or may not be duplicated in the next 100,000 examinations. The cause of death in some patients may be related to a combination of factors— primary disease, diagnostic procedure, and contrast medium.The over...

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