Loss-Of-Function Alleles of the JIL-1 Kinase Are Strong Suppressors of Position Effect Variegation of the wm4 Allele in Drosophila
- 1 August 2006
- journal article
- review article
- Published by Oxford University Press (OUP) in Genetics
- Vol. 173 (4) , 2403-2406
- https://doi.org/10.1534/genetics.106.059253
Abstract
In this article we show that hypomorphic loss-of-function alleles of the JIL-1 histone H3S10 kinase are strong suppressors of position effect variegation (PEV) of the wm4 allele and that lack of JIL-1 activity can counteract the effect of the dominant enhancer E(var)2-1 on PEV.Keywords
This publication has 15 references indexed in Scilit:
- The JIL-1 histone H3S10 kinase regulates dimethyl H3K9 modifications and heterochromatic spreading inDrosophilaDevelopment, 2006
- The JIL-1 kinase regulates the structure of Drosophila polytene chromosomesChromosoma, 2005
- Su(var) genes regulate the balance between euchromatin and heterochromatin in DrosophilaGenes & Development, 2004
- Increased expression ofDrosophilaSu(var)3-7 triggers Su(var)3-9-dependent heterochromatin formationJournal of Cell Science, 2004
- Genetic and Phenotypic Analysis of Alleles of the Drosophila Chromosomal JIL-1 Kinase Reveals a Functional Requirement at Multiple Developmental StagesGenetics, 2003
- Heterochromatin function in complex genomesBiochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2000
- JIL-1Molecular Cell, 1999
- HETEROCHROMATIN AND GENE EXPRESSION IN DROSOPHILAAnnual Review of Genetics, 1995
- Variegation in Drosophila and the Inert Chromosome RegionsProceedings of the National Academy of Sciences, 1936
- Types of visible variations induced by X-rays inDrosophilaJournal of Genetics, 1930