Studies on the pregnenolone-16α-carbonitrile-inducible form of rat liver microsomal cytochrome P-450 and UDP-glucuronosyltransferase
- 4 November 1987
- journal article
- research article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 36 (22) , 3859-3866
- https://doi.org/10.1016/0006-2952(87)90450-3
Abstract
No abstract availableKeywords
This publication has 35 references indexed in Scilit:
- Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymesBiochemistry, 1985
- Age- and sex-dependent induction of liver microsomal benzo[a]pyrene hydroxylase activity in rats treated with pregnenolone-16α-carbonitrile (PCN)Carcinogenesis: Integrative Cancer Research, 1985
- Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or .beta.-naphthoflavoneBiochemistry, 1982
- On the substrate specificity of the digitoxigenin monodigitoxoside conjugating UDP-glucuronyltransferase in rat liverBiochemical Pharmacology, 1982
- Glucuronidation of digitalis glycosides by rat liver microsomes: Stimulation by spironolactone and pregnenolone-16α-carbonitrileBiochemical Pharmacology, 1980
- Stimulation of the glucuronidation of digitoxigenin-monodigitoxoside by liver homogenates from spironolactone-pretreated ratsToxicology and Applied Pharmacology, 1977
- Pregnenolone-16α-carbonitrile: A new type of inducer of drug-metabolizing enzymesArchives of Biochemistry and Biophysics, 1972
- Effect of pretreatment with spironolactone, phenobarbital or β-diethylaminoethyl diphenylpropyl-acetate (SKF 525-A) on tritium levels in blood, heart and liver of rats at various times after administration of [3H]digitoxinBiochemical Pharmacology, 1972
- Protection by spironolactone and oxandrolone against chronic digitoxin or indomethacin intoxicationToxicology and Applied Pharmacology, 1971
- Hormones and ResistanceJournal of Pharmaceutical Sciences, 1971