Determination of Diamine Oxidase Activity in Normal Human Blood Serum

Abstract
The method with 14C-putrescine as the substrate for routine measurement of serum (plasma) diamine oxidase (histaminase) during pregnancy, and mola hydatidosa (chorionepitelioma) has been modified. The optimal experimental conditions for determination of diamine oxidase (DAO) activity in normal human blood serum are given. Normal range for serum DAO is 0 to 20 mU/1. The majority, however, grouped around 4 mU/1, i.e., about 1/500 of the serum DAO activity in the last trimester of normal pregnancy.

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