DETECTION BY ELISA OF IGM ANTIBODIES TO ROSS RIVER VIRUS IN SERUM FROM PATIENTS WITH SUSPECTED EPIDEMIC POLYARTHRITIS

1 January 1983

journal article
research article

Vol. 61 (4) , 703-708

Abstract

An ELISA [enzyme-linked immunosorbent assay] method for the detection of IgM antibody to Ross River virus in the serum of patients with suspected epidemic polyarthritis was developed. None of the reagents is infectious or toxic and the use of purified virus minimizes the risk of nonspecific reactions to nonviral products. In a positive reaction the ELISA substrate changes color from yellow to purple, enabling serum antibody titers to be read by eye.

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