Urokinase treatment of pulmonary artery thrombosis complicating the pediatric nephrotic syndrome
- 1 February 1985
- journal article
- case report
- Published by Wolters Kluwer Health in Critical Care Medicine
- Vol. 13 (2) , 132-134
- https://doi.org/10.1097/00003246-198502000-00018
Abstract
Two pediatric patients with severe pulmonary thrombosis complicating a lipoid nephrosis were treated with urokinase administered either as a continuous infusion or in massive bolus doses. Both patients recovered but one died suddenly 2 yr later after recurrence of the nephrotic syndrome and probably new massive pulmonary thrombosis. These patients had severe abnormalities of hemostasis and fibrinolysis, which favored thrombosis and complicated fibrinolytic treatment.Keywords
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