Radiation-Induced Splenic Atrophy in Patients with Hodgkin's Disease and Non-Hodgkin's Lymphomas

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Abstract
Effective treatment of Hodgkin's disease renation of the extent of the disease. This usually involves staging laparotomy, which includes splenectomy and biopsies of the para-aortic lymph nodes, liver, and bone marrow. Absence of the spleen predisposes a person to fulminant septicemia from encapsulated bacteria, a risk even greater in patients undergoing treatment for Hodgkin's disease.1 For this reason, some investigators have suggested that spleens not be removed for diagnosis but, rather, that they be included within the fields of radiation, which would preserve normal splenic function.2 , 3 We present a case of fatal spontaneous pneumococcal sepsis in a patient with splenic . . .

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