ACID‐BASE CHANGES UNDER HALOTHANE, NITROUS OXIDE AND OXYGEN ANAESTHESIA DURING SPONTANEOUS RESPIRATION
- 9 December 1960
- journal article
- Published by Wiley in Acta Anaesthesiologica Scandinavica
- Vol. 4 (4) , 173-180
- https://doi.org/10.1111/j.1399-6576.1960.tb00072.x
Abstract
SUMMARY: The effects of 1.5 per cent. halothane on respiration in patients undergoing surgery were studied by means of assessing the acid‐base status of arterial blood. The depression of spontaneous respiration and rise in carbon dioxide tension were found to be less than earlier reported during halothane anaesthesia without concomitant surgery. Earlier findings that halothane does not cause metabolic acidosis in patients under controlled respiration were confirmed in patients allowed to breathe spontaneously. The effect of halothane on the metabolic rate is discussed.ZUSAMMENFASSUNG: Bei einer Anzahl von Patienten wurde intraoperativ die Wirkung einer Konzentration von 1,5% Halothan auf die Atmung mit Hilfe der Bestimmung des Säure‐Basen‐Status im arteriellen Blut untersucht. Die Dämpfung der Spontanatmung und der Anstieg der Kohlensäurespannung war geringer als bei früheren Studien die während der Halothannarkose, jedoch ohne gleichzeitigen chirurgischen Eingriff, durchgeführt worden waren. Die früheren Befunde, dass Halothan bei Patienten mit kontrollierter Beatmung keine metabolische Acidose hervorruft, konnten an spontanatmenden Patienten bestätigt werden. Die Wirkung von Halothan auf den Grundumsatz wird diskutiert.Keywords
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