ACUTE HEMOLYTIC ANEMIA ASSOCIATED WITH MYELOID METAPLASIA OF THE SPLEEN
- 1 March 1952
- journal article
- research article
- Published by American Medical Association (AMA) in A.M.A. Archives of Internal Medicine
- Vol. 89 (3) , 431-435
- https://doi.org/10.1001/archinte.1952.00240030080009
Abstract
SINCE the description of Jackson and associates1of myeloid metaplasia, there have been numerous case reports concerning this disease in its primary and secondary forms. These cases have been divided into two predominant groups: the one resulting from bone marrow replacement on the basis of malignant growth or fibrosis, the other being primary or agnogenic. It has been reported in association with carcinoma metastatic to bone and with infectious states, such as scarlet fever, and in cases of generalized sepsis, tuberculosis of spleen, and idiopathic osteosclerosis. It has frequently been reported as bearing relationship to acquired hemolytic anemia. Those cases showing clinical and laboratory evidence of hemolytic anemia have been, as far as we have been able to ascertain, without exception chronic.2We have recently had occasion to observe a case with microscopic evidence of marked myeloid metaplasia of the spleen and exhibiting an acute clinical course characterizedThis publication has 0 references indexed in Scilit: