THE NEUROPATHY OF MULTIPLE MYELOMA
Open Access
- 1 May 1958
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 21 (2) , 73-88
- https://doi.org/10.1136/jnnp.21.2.73
Abstract
Polyneuropathy in multiple myeloma, not dependent on compression by tumor tissue, was studied in 5 cases. The polyneuropathy appeared as a symmetrical, atrophic, areflexic, sensorimotor affection of the legs or arms. The cerebrospinal fluid protein level was elevated in 4 patients and in 3 the symptoms preceded those of multiple myeloma. There was degeneration of both axis cylinder and myelin sheath of the peripheral nerves in the more distal segments.Keywords
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