Blood Coagulation in Pregnancy

Publisher Website
Google Scholar
Abstract
ALTHOUGH thromboembolism has frequently been attributed to abnormal blood coagulation, convincing evidence for this concept has been lacking. The disclosure of hitherto unrecognized coagulation factors and the development of methods for their assay prompted re-examination of this question. Pregnancy was selected as the initial area of study because it constitutes a common, temporary, reversible, physiologic state that is too frequently complicated by thromboembolism. This report presents data indicating that during pregnancy abnormally high levels of at least one important clotting constituent do develop, returning to normal in most cases after term. It is proposed that these changes reflect a state . . .