Incidence, Epidemiology, and Characteristics of Quinolone- Nonsusceptible Streptococcus pneumoniae in Croatia

Abstract
Among 585 Streptococcus pneumoniae strains isolated in 22 Croatian hospitals 21 strains (3.6%) were quinolone nonsusceptible. MICs of all quinolones were high for seven strains tested with the same serotype (23F) and mutations in gyrA , parC , and parE . The remaining 14 strains were more heterogeneous and had mutations only in parC and/or parE , and the MICs of quinolones were lower for these strains.

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