ShoRAH: estimating the genetic diversity of a mixed sample from next-generation sequencing data
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Open Access
- 26 April 2011
- journal article
- Published by Springer Nature in BMC Bioinformatics
- Vol. 12 (1) , 119
- https://doi.org/10.1186/1471-2105-12-119
Abstract
With next-generation sequencing technologies, experiments that were considered prohibitive only a few years ago are now possible. However, while these technologies have the ability to produce enormous volumes of data, the sequence reads are prone to error. This poses fundamental hurdles when genetic diversity is investigated.Keywords
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