Comparison of Two Ultrashort Duration Anesthetic Agents

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Abstract
Comparison of 2 epinephrine free solutions, mepivacaine 3% and L67 (prilocaine) 4% was carried out using author''s minimum dosage technique over 5 areas in the mouth; Upper; incisor, canine, premolar and molar, and lower; mental block. Comparison was made for parameters using criteria laid down in previous work especially 4[image] 30[image] time limit for successful onset time of anesthesia. Mepivacaine 3% had the following data: Onset time 2[image] 30[image], extent 3.7 units (1 unit = width of a premolar) Duration 1 hour, efficiency 82%, for a mean dose of 0.75 ml. L67 4% showed: Onset time 2[image] 40[image], extent 2.6 units, duration 1 hour, efficiency 94% for a mean dose of 0.6 ml. It was clear that since there were no toxic effects whatever with either drug, the greater efficency rate of the 4% L67 and the smaller dosage made it the more valuable solution for ultrashort anesthesia, that is where not more than 7-10 minutes working time was required. The value of both of these solutions lies in the lessening of danger from lip biting, and the elimination of the annoyance of "rubbery lip" for 3 hours after a 5 minute session.

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