In vitroAnti-Helicobacter pylori Activity of Some Flavonoids and Their Metabolites
- 1 June 1999
- journal article
- letter
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 65 (05) , 442-443
- https://doi.org/10.1055/s-2006-960805
Abstract
The inhibitory effect of flavonoids and phenolic acids, which could be transformed from flavonoids by human intestinal microflora, on the growth of Helicobocter pylori (HP) was investigated. Ponciretin, hesperetin, naringenin and diosmetin were active against HP. Among them, ponciretin was the most potent and its MIC was 10-20 µg/ml. However, these active compounds against HP did nearly not inhibit the urease activity of HP.Keywords
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