Lidocaine's Influence on the Accumulation and Depletion Rates of Mouse Brain Amines
- 1 November 1977
- journal article
- research article
- Published by SAGE Publications in Journal of Dental Research
- Vol. 56 (11) , 1391-1394
- https://doi.org/10.1177/00220345770560111901
Abstract
Mouse brain was analyzed for serotonin, norepinephrine, and dopamine. Pargyline plus lidocaine treatment caused an increased accumulation rate of serotonin over one hour compared to pargyline controls. α Methyl-p-tyrosine plus lidocaine treatment caused a decreased depletion rate of dopamine over four hours compared to rates of α methyl-p-tyrosine controls, and no difference for norepinephrine.Keywords
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