Strychnine- and Pentylenetetrazol-Induced Changes of Excitability in Aplysia Neurons
- 16 March 1973
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 179 (4078) , 1133-1136
- https://doi.org/10.1126/science.179.4078.1133
Abstract
In Aplysia neurons isolated from their synaptic input strychnine induces doublet discharges associated in voltage clamp with a decrease in the threshold for the inward current and a reduction and delayed onset of the outward current. Pentylenetetrazol causes oscillations and bursting behavior in normally silent cells together with an increased inactivation of the delayed outward current and induced or enhanced anomalous rectification.Keywords
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