PD 114,759 and PD 115,028, novel antitumor antibiotics with phenomenal potency. I. Isolation and characterization.

1 January 1984

journal article
research article
Published by Japan Antibiotics Research Association in The Journal of Antibiotics

Vol. 37 (12) , 1566-1571
https://doi.org/10.7164/antibiotics.37.1566

Abstract

The isolation of 2 new antibiotics, PD 114,759 and PD 115,028, exhibiting in vivo antitumor activity at extremely low doses is described. The physicochemical properties of these S-containing compounds show that they represent a novel class of antitumor agents.