The relationship between T-lymphocyte subset infiltration and survival in patients with prostate cancer
Open Access
- 13 July 2004
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 91 (3) , 541-543
- https://doi.org/10.1038/sj.bjc.6601943
Abstract
The relationship between tumour stage, T-lymphocyte subset infiltration and survival was examined in patients with prostate cancer (n=80). On multivariate analysis PSA (HR 2.47, 95% CI 1.27–4.83, P=0.008) and CD4+ T-lymphocyte count (HR 2.29, 95% CI 1.25–4.22, P=0.008) had independent significance. Increased CD4+ T-lymphocyte infiltration within the tumour was stage independent and associated with poor outcome in patients with prostate cancer.Keywords
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