Treatment of Lupus Interstitial Lung Disease with Intravenous Cyclophosphamide
- 1 March 1994
- journal article
- case report
- Published by Wiley in Arthritis & Rheumatism
- Vol. 37 (3) , 428-431
- https://doi.org/10.1002/art.1780370318
Abstract
Intravenous pulse cyclophosphamide (IPC) was used to treat lupus interstitial lung disease in 2 patients. Vital capacity increased by 67–110% of baseline values with IPC treatment. Total lung capacity and diffusing capacity also improved. Dyspnea and other manifestations of lupus improved dramatically. This is the first report documenting the efficacy of the early use of IPC for acute and chronic interstitial lung disease associated with lupus.Keywords
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