INFLUENCE OF OXYTOCIN (PITOCIN) UPON THE HEART AND BLOOD PRESSURE OF THE CHICKEN, RABBIT, CAT, DOG AND TURTLE

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Abstract
The oxytocic fraction of post. pituitary preps. has cardiovascular actions. The species'' variation of these effects is pronounced. These changes are not those produced by the vasopressor principle and do not arise from a reduced coronary flow. In the rabbit and cat intraven. adms. of pituitary preps. which contain the oxytocic fractions lower the arterial pressure and markedly weaken cardiac contractions as in man. Also vasodilatation often occurs in the rabbit and cat as in the chicken. In the turtle, the transient reduction in the blood pressure arises mainly from peripheral vasodilatation as in the chicken. The oxytocic fraction does not lower the blood pressure in normal dogs.

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