Abstract
(1) As a sequel to epidemiological studies of malaria in a low-lying coastal region of Tanganyika in 1952, further similar observations were carried out at an altitude of 3,500 feet in Uganda in 1953. (2) Malaria was holo-endemic and the inoculation rate, derived from parasite indices, estimated at about one infection every 2 months. (3) The densities of the vector mosquitoes, A. gambiae and A. funestus, were comparatively low but their infection rates high. The estimated inoculation rate from entomological data was of the order of one infection every 3 days. (4) Survival rates of the vector species, estimated by two different methods, were high especially in A. gambiae. (5) An analysis on numerical lines of the transmission of malaria in the district under study has been made and the implications of the findings in relation to control by insecticides are discussed.

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