Convergent Syntheses of the Enantiomeric CD- and JK-Ring Parts of Ciguatoxin

Abstract
Convergent syntheses of the enantiomeric CD- and JK-ring parts of ciguatoxin, based on a coupling reaction between dithioacetal mono-S-oxide and aldehyde derivatives and reductive cyclization of the respective hydroxy ketones, have been achieved.

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