CARDIAC MAN IFESTATIONS OF CONGENITAL HYPOTHYROIDISM IN INFANTS

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Abstract
1. The cardiovascular status of 40 patients under 6 months of age with uncomplicated congenital hypothyroidism was studied. 2. A significant number of these infants presented with symptoms which suggested cardiovascular disease. 3. The majority had heart murmurs and x-ray and electrocardiographic changes on admission, but these disappeared rapidly, in almost all instances, shortly after onset of thyroid therapy. 4. Autopsy findings in two infants with hypothyroidism and heart murmurs, as well as cardiac catheterization of two patients, failed to shed light on the etiology of the cardiac findings.

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