Oxidative Desulfurization-Fluorination of Methyl Arenedithiocarboxylates. A Convenient Synthesis of Trifluoromethylated Aromatic Compounds
- 1 May 1992
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 21 (5) , 827-830
- https://doi.org/10.1246/cl.1992.827
Abstract
Trifluoromethyl-substituted aromatic compounds were obtained by oxidative desulfurization-fluorination reaction of methyl arenedithiocarboxylates using n-Bu4N+H2F3>− and 1,3-dibromo-5,5-dimethylhydantoin (DBH). Use of N-bromosuccinimide or N-iodosuccinimide instead of DBH afforded difluoro(methylthio)methyl-substituted aromatics.This publication has 10 references indexed in Scilit:
- Directed ortho metalation. Tertiary amide and O-carbamate directors in synthetic strategies for polysubstituted aromaticsChemical Reviews, 1990
- A new method of introducing a trifluoromethyl group into an aromatic ringTetrahedron Letters, 1990
- A facile synthesis of aromatic trifluoromethyl compounds via orthothio estersTetrahedron Letters, 1986
- Pregeneration, spectroscopic detection and chemical reactivity of (trifluoromethyl)copper, an elusive and complex speciesJournal of the American Chemical Society, 1986
- Synthesis and Reactivity of N-Trifluoromethyl-N-nitrosotrifluoromethanesulfonamide as a New Type of Trifluoromethylating AgentBulletin of the Chemical Society of Japan, 1986
- A new method for the trifluoromethylation of aromaticsJournal of Fluorine Chemistry, 1981
- Published by American Chemical Society (ACS) ,1978
- Studies on the organic fluorine compounds. XXIV. Photochemical trifluoromethylation of aromatic compounds.CHEMICAL & PHARMACEUTICAL BULLETIN, 1978
- The Chemistry of Sulfur Tetrafluoride. II. The Fluorination of Organic Carbonyl Compounds1Journal of the American Chemical Society, 1960
- Preparation of m-FluorobenzotrifluorideJournal of the American Chemical Society, 1934