Oily Barbarians Breach Ion Channel Gates
- 9 April 2004
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 304 (5668) , 223-224
- https://doi.org/10.1126/science.1097439
Abstract
It has long been debated whether and how voltage-gated ion channels are affected by the lipid environment of the plasma membrane. In his Perspective, Hilgemann discusses new work ( Oliver et al.) showing that the inactivation of voltage-gated potassium (Kv) channels can be modulated by the lipids PIPand arachidonic acid.Keywords
This publication has 26 references indexed in Scilit:
- Enhancement of Phototransduction G Protein-Effector Interactions by PhosphoinositidesPublished by Elsevier ,2004
- Genistein Can Modulate Channel Function by a Phosphorylation-Independent Mechanism: Importance of Hydrophobic Mismatch and Bilayer MechanicsBiochemistry, 2003
- Intrinsic Tyrosine Fluorescence as a Tool To Study the Interaction of the Shaker B “Ball” Peptide with Anionic MembranesBiochemistry, 2003
- X-ray structure of a voltage-dependent K+ channelNature, 2003
- Regulation of TRP Channels via Lipid Second MessengersAnnual Review of Physiology, 2003
- Recovery from Muscarinic Modulation of M Current Channels Requires Phosphatidylinositol 4,5-Bisphosphate SynthesisNeuron, 2002
- Structural and Functional Determinants of Conserved Lipid Interaction Domains of Inward Rectifying Kir6.2 ChannelsThe Journal of general physiology, 2002
- Inactivation of IA Channels of Frog Skeletal Muscle Is Modulated by ATPBiochemical and Biophysical Research Communications, 2002
- Eicosanoids Inhibit the G-protein-gated Inwardly Rectifying Potassium Channel (Kir3) at the Na+/PIP2 Gating SiteJournal of Biological Chemistry, 2001
- Steady-state and dynamic properties of cardiac sodium-calcium exchange. Sodium-dependent inactivation.The Journal of general physiology, 1992