Histopathological evaluation of hyperthermochemo radiotherapy for carcinoma of the esophagus

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Abstract
The effectiveness of preoperative hyperthermo‐chemo‐radiotherapy for 25 patients with carcinoma of the esophagus was histopathologically compared with findings in 104 patients treated preoperatively with irradiation only. The preoperative hyperthermo‐chemo‐radiotherapy increased the rate of “markedly effective” in the resected tissue, when compared with findings in cases of irradiation only. With regard to long survival rates, The 5‐year survival rates of patients classed as “markedly effective” with preoperative combined therapy exceeded events in patients classed as “moderately effective,” and “ineffective,” with statistical significance. Preoperative hyperthermo‐chemo‐radiotherapy is the recommended treatment for patients with carcinoma of the esophagus.